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Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions

We examine how collagen substrate topography, free intracellular calcium ion concentration ([Ca(2+)](i), and the association of gelsolin with nonmuscle myosin IIA (NMMIIA) at collagen adhesions are regulated to enable collagen phagocytosis. Fibroblasts plated on planar, collagen-coated substrates sh...

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Hlavní autoři: Arora, P. D., Wang, Y., Bresnick, A., Dawson, J., Janmey, P. A., McCulloch, C. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596245/
https://ncbi.nlm.nih.gov/pubmed/23325791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0754
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