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Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion

Tumours evolve several mechanisms to evade apoptosis, yet many resected carcinomas show significantly elevated caspase activity. Moreover, caspase activity is positively correlated with tumour aggression and adverse patient outcome. These observations indicate that caspases might have a functional r...

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Détails bibliographiques
Auteurs principaux: Rudrapatna, Vivek A, Bangi, Erdem, Cagan, Ross L
Format: Artigo
Langue:Inglês
Publié: European Molecular Biology Organization 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596137/
https://ncbi.nlm.nih.gov/pubmed/23306653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.217
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