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Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion

Tumours evolve several mechanisms to evade apoptosis, yet many resected carcinomas show significantly elevated caspase activity. Moreover, caspase activity is positively correlated with tumour aggression and adverse patient outcome. These observations indicate that caspases might have a functional r...

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Detalhes bibliográficos
Main Authors: Rudrapatna, Vivek A, Bangi, Erdem, Cagan, Ross L
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596137/
https://ncbi.nlm.nih.gov/pubmed/23306653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.217
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