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The yeast rad18 mutator specifically increases G.C----T.A transversions without reducing correction of G-A or C-T mismatches to G.C pairs.

Inactivation of the Saccharomyces cerevisiae RAD18 gene confers a mutator phenotype. To determine the specificity of this effect, a collection of 212 spontaneous SUP4-o mutants arising in a rad18 strain was characterized by DNA sequencing. Comparison of the resulting mutational spectrum with that fo...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Kunz, B A, Kang, X L, Kohalmi, L
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359612/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.218
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