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Cisplatin and Aminoglycoside Antibiotics: Hearing Loss and Its Prevention

This review introduces the pathology of aminoglycoside antibiotic and the cisplatin chemotherapy classes of drugs, discusses oxidative stress in the inner ear as a primary trigger for cell damage, and delineates the ensuing cell death pathways. Among potentially ototoxic (damaging the inner ear) the...

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Detalhes bibliográficos
Main Authors: Schacht, Jochen, Talaska, Andra E., Rybak, Leonard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596108/
https://ncbi.nlm.nih.gov/pubmed/23045231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.22578
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