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Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles

A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide–internal alkyne 1,3-dipolar cycloaddition domino sequence has been described. The efficacy of the method...

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Main Authors: Arigela, Rajesh K, Sharma, Sudhir K, Kumar, Brijesh, Kundu, Bijoy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Beilstein-Institut 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596043/
https://ncbi.nlm.nih.gov/pubmed/23504610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.41
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