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How Samhd1 changes our view of viral restriction
Recent studies have uncovered sterile alpha motif and HD domain 1 (SAMHD1) as the restriction factor that blocks HIV-1 replication in myeloid cells. In contrast to previously identified HIV-1 restriction factors, SAMHD1 does not meet a countermeasure developed by HIV-1. However, HIV-2 and certain si...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595995/ https://ncbi.nlm.nih.gov/pubmed/22177690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.11.002 |
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