Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells.
Inactivation of the cellular p53 gene is a common feature of Friend virus-induced murine erythroleukemia cell lines and may represent a necessary step in the progression of this disease. As well, frequent loss or mutation of p53 alleles in diverse human tumors is consistent with the view of p53 as a...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.1-11.1991 |
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