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Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells.

Inactivation of the cellular p53 gene is a common feature of Friend virus-induced murine erythroleukemia cell lines and may represent a necessary step in the progression of this disease. As well, frequent loss or mutation of p53 alleles in diverse human tumors is consistent with the view of p53 as a...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Johnson, P, Gray, D, Mowat, M, Benchimol, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986214/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.1
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