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Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis
Apoptosis occurs through a tightly regulated cascade of caspase activation. In the context of extrinsic apoptosis, caspase-8 is activated by dimerization inside a death receptor complex, cleaved by auto-proteolysis and subsequently released into the cytosol. This fully processed form of caspase-8 is...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595484/ https://ncbi.nlm.nih.gov/pubmed/23306557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.156 |
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