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FANCM and FAAP24 Maintain Genome Stability via Cooperative as well as Unique Functions
The DNA remodeling enzyme FANCM and its DNA-binding partner, FAAP24, constitute a complex involved in the activation of Fanconi Anemia (FA) DNA damage response mechanism, but neither gene has distinct patient mutants. In this study, we created isogenic models for both FANCM and FAAP24 and investigat...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595374/ https://ncbi.nlm.nih.gov/pubmed/23333308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.010 |
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