FANCM and FAAP24 Maintain Genome Stability via Cooperative as well as Unique Functions

The DNA remodeling enzyme FANCM and its DNA-binding partner, FAAP24, constitute a complex involved in the activation of Fanconi Anemia (FA) DNA damage response mechanism, but neither gene has distinct patient mutants. In this study, we created isogenic models for both FANCM and FAAP24 and investigat...

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Main Authors: Wang, Yucai, Leung, Justin W., Jiang, Yingjun, Lowery, Megan G., Huong, Do, Vasquez, Karen M., Chen, Junjie, Wang, Weidong, Li, Lei
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595374/
https://ncbi.nlm.nih.gov/pubmed/23333308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.010
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