Interleukin-27 Signaling Promotes Immunity against Endogenously Arising Murine Tumors

Interleukin-27 (IL-27) is a pleiotropic cytokine but its immunosuppressive effects predominate during many in vivo immunological challenges. Despite this, evidence from tumor cell line transfer models suggested that IL-27 could promote immune responses in the tumor context. However, the role of IL-2...

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Main Authors: Natividad, Karlo D. T., Junankar, Simon R., Mohd Redzwan, Norhanani, Nair, Radhika, Wirasinha, Rushika C., King, Cecile, Brink, Robert, Swarbrick, Alexander, Batten, Marcel
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595259/
https://ncbi.nlm.nih.gov/pubmed/23554861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057469
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