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Drosophila Bestrophin-1 Currents Are Regulated by Phosphorylation via a CaMKII Dependent Mechanism

Cell swelling induced by hypo-osmotic stress results in activation of volume-regulated anion channels (VRAC) that drive a compensatory regulatory volume decrease. We have previously shown that the Best1 gene in Drosophila encodes a VRAC that is also activated by increases in intracellular Ca(2+). Th...

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Autors principals: Duran, Charity, Chien, Li-Ting, Hartzell, H. Criss
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595206/
https://ncbi.nlm.nih.gov/pubmed/23554946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058875
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