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Rescue of Volume-regulated Anion Current by Bestrophin Mutants with Altered Charge Selectivity
Mutations in human bestrophin-1 are linked to various kinds of retinal degeneration. Although it has been proposed that bestrophins are Ca(2+)-activated Cl(−) channels, definitive proof is lacking partly because mice with the bestrophin-1 gene deleted have normal Ca(2+)-activated Cl(−) currents. Her...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571971/ https://ncbi.nlm.nih.gov/pubmed/18955594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810065 |
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