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α–SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKα in vitro

The AMP-activated protein kinase (AMPK) regulates metabolism in normal and pathological conditions and responds to nutrients, hormones, anti-diabetic drugs and physical exercise. AMPK is activated by kinase LKB1 and inactivated by phosphatases whose identities remain uncertain. Here we show that AMP...

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Bibliografski detalji
Glavni autori: Wang, Lifu, Brautigan, David L.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595137/
https://ncbi.nlm.nih.gov/pubmed/23463002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2565
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