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Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

Starvation of the yeast Saccharomyces cerevisiae for an amino acid signals increased translation of GCN4, a transcriptional activator of amino acid biosynthetic genes. We have isolated and characterized the GCD6 and GCD7 genes and shown that their products are required to repress GCN4 translation un...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Bushman, J L, Asuru, A I, Matts, R L, Hinnebusch, A G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1920-1932.1993
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