Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

Starvation of the yeast Saccharomyces cerevisiae for an amino acid signals increased translation of GCN4, a transcriptional activator of amino acid biosynthetic genes. We have isolated and characterized the GCD6 and GCD7 genes and shown that their products are required to repress GCN4 translation un...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Bushman, J L, Asuru, A I, Matts, R L, Hinnebusch, A G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1920-1932.1993
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