Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

Starvation of the yeast Saccharomyces cerevisiae for an amino acid signals increased translation of GCN4, a transcriptional activator of amino acid biosynthetic genes. We have isolated and characterized the GCD6 and GCD7 genes and shown that their products are required to repress GCN4 translation un...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Bushman, J L, Asuru, A I, Matts, R L, Hinnebusch, A G
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1920
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