Intraspecific Evolution of Human RCCX Copy Number Variation Traced by Haplotypes of the CYP21A2 Gene

The RCCX region is a complex, multiallelic, tandem copy number variation (CNV). Two complete genes, complement component 4 (C4) and steroid 21-hydroxylase (CYP21A2, formerly CYP21B), reside in its variable region. RCCX is prone to nonallelic homologous recombination (NAHR) such as unequal crossover,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bánlaki, Zsófia, Szabó, Julianna Anna, Szilágyi, Ágnes, Patócs, Attila, Prohászka, Zoltán, Füst, George, Doleschall, Márton
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595039/
https://ncbi.nlm.nih.gov/pubmed/23241443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs121
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky