The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome.

Ítems similars

• Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.
  per: Tarn, W Y, et al.
  Publicat: (1993)
• Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing.
  per: Kim, S H, et al.
  Publicat: (1996)
• Differential nuclease sensitivity identifies tight contacts between yeast pre-mRNA and spliceosomes.
  per: Rymond, B C, et al.
  Publicat: (1986)
• Early commitment of yeast pre-mRNA to the spliceosome pathway.
  per: Legrain, P, et al.
  Publicat: (1988)
• Commitment of yeast pre-mRNA to the splicing pathway requires a novel U1 small nuclear ribonucleoprotein polypeptide, Prp39p.
  per: Lockhart, S R, et al.
  Publicat: (1994)