Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein.

During progression of Moloney murine leukemia virus (Mo-MuLV)-induced rat T cell lymphomas, growth selection results in the expansion of cell clones carrying increasing numbers of integrated proviruses. These new provirus insertions reproducibly contribute to enhanced growth, allowing the emergence...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Gilks, C B, Bear, S E, Grimes, H L, Tsichlis, P N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441411/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1759-1768.1993
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