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SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion

The S2 domain of the coronavirus spike (S) protein is known to be responsible for mediating membrane fusion. In addition to a well-recognized cleavage site at the S1–S2 boundary, a second proteolytic cleavage site has been identified in the severe acute respiratory syndrome coronavirus (SARS-CoV) S2...

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Bibliografiske detaljer
Main Authors: Madu, Ikenna G., Belouzard, Sandrine, Whittaker, Gary R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594805/
https://ncbi.nlm.nih.gov/pubmed/19717178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.07.038
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