(18)F-FDG PET/CT Imaging Detects Therapy Efficacy of Anti-EMMPRIN Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts

PURPOSE: To evaluate by sequential (18)F-FDG PET/CT imaging the therapeutic response to a novel monoclonal antibody targeting human EMMPRIN (extracellular matrix metalloproteinase inducer) in combination with gemcitabine in a pancreatic-tumor xenograft murine model. PROCEDURES: Four groups of SCID m...

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Main Authors: Shah, Nemil, Zhai, Guihua, Knowles, Joseph A., Stockard, Cecil R., Grizzle, William E., Fineberg, Naomi, Zhou, Tong, Zinn, Kurt R., Rosenthal, Eben L., Kim, Hyunki
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594775/
https://ncbi.nlm.nih.gov/pubmed/21494920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0491-5
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