hCAF1/CNOT7 regulates interferon signalling by targeting STAT1

Stringent regulation of the interferon (IFN) signalling pathway is essential for maintaining the immune response to pathogens and tumours. The transcription factor STAT1 is a crucial mediator of this response. Here, we show that hCAF1/CNOT7 regulates class I and II IFN pathways at different crucial...

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Autores principales: Chapat, Clément, Kolytcheff, Chloé, Le Romancer, Muriel, Auboeuf, Didier, De La Grange, Pierre, Chettab, Kamel, Sentis, Stéphanie, Corbo, Laura
Formato: Artigo
Lenguaje:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594750/
https://ncbi.nlm.nih.gov/pubmed/23386060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.11
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