hCAF1/CNOT7 regulates interferon signalling by targeting STAT1

Stringent regulation of the interferon (IFN) signalling pathway is essential for maintaining the immune response to pathogens and tumours. The transcription factor STAT1 is a crucial mediator of this response. Here, we show that hCAF1/CNOT7 regulates class I and II IFN pathways at different crucial...

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Detalhes bibliográficos
Main Authors: Chapat, Clément, Kolytcheff, Chloé, Le Romancer, Muriel, Auboeuf, Didier, De La Grange, Pierre, Chettab, Kamel, Sentis, Stéphanie, Corbo, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594750/
https://ncbi.nlm.nih.gov/pubmed/23386060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.11
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