Functional analysis of developmentally regulated chromatin-hypersensitive domains carrying the alpha 1-fetoprotein gene promoter and the albumin/alpha 1-fetoprotein intergenic enhancer.

During liver development, the tandem alpha 1-fetoprotein (AFP)/albumin locus is triggered at the AFP end and then asymmetrically enhanced; this is followed by autonomous repression of the AFP-encoding gene. To understand this regulation better, we characterized the two early developmental stage-spec...

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Detalhes bibliográficos
Main Authors: Bernier, D, Thomassin, H, Allard, D, Guertin, M, Hamel, D, Blaquière, M, Beauchemin, M, LaRue, H, Estable-Puig, M, Bélanger, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359474/
https://ncbi.nlm.nih.gov/pubmed/7680097
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