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Nonimmune thyroid destruction results from transgenic overexpression of an allogeneic major histocompatibility complex class I protein.

The overexpression of major histocompatibility complex (MHC) class I molecules in endocrine epithelial cells is an early feature of autoimmune thyroid disease and insulin-dependent diabetes mellitus, which may reflect a cellular response, e.g., to viruses or toxins. Evidence from a transgenic model...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Frauman, A G, Chu, P, Harrison, L C
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1554-1564.1993
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