Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2 and IL-6

PURPOSE: Invasion is the critical step in progression of a pre-cancerous lesion to squamous cell carcinoma of the head and neck (SCCHN). Invasion is regulated by multiple pro-inflammatory mediators. Tristetraprolin (TTP) is an mRNA degrading protein that regulates multiple pro-inflammatory mediators...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Van Tubergen, Elizabeth A., Banerjee, Rajat, Liu, Min, Broek, Robert Vander, Light, Emily, Kuo, Shiuhyang, Feinberg, Stephen E., Willis, Amanda L., Wolf, Gregory, Carey, Thomas, Bradford, Carol, Prince, Mark, Worden, Francis P., Kirkwood, Keith L., D’Silva, Nisha J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594656/
https://ncbi.nlm.nih.gov/pubmed/23349315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2927
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