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B1a cells enhance susceptibility to infection with virulent Francisella tularensis via modulation of NK/NKT cell responses

B1a cells are an important source of natural antibodies, antibodies directed against T-independent antigens, and are a primary source of IL-10. Bruton's tyrosine kinase (btk) is a cytoplasmic kinase that is essential for mediating signals from the B cell receptor and is critical for development...

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Библиографические подробности
Главные авторы: Crane, Deborah D., Griffin, Amanda J., Wehrly, Tara D., Bosio, Catharine M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594638/
https://ncbi.nlm.nih.gov/pubmed/23378429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202697
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