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Long-term antibody memory induced by synthetic peptide vaccination is protective against Streptococcus pyogenes infection and is independent of memory T-cell help

Streptococcus pyogenes (group A streptococcus; GAS) is a leading human pathogen associated with a diverse array of mucosal and systemic infections. Vaccination with J8, a conserved region synthetic peptide derived from the M-protein of GAS and containing only 12 amino acids from GAS, when conjugated...

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Detalhes bibliográficos
Main Authors: Pandey, Manisha, Wykes, Michelle N, Hartas, Jon, Good, Michael F, Batzloff, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594626/
https://ncbi.nlm.nih.gov/pubmed/23401589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202333
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