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Mechanism of Protection Induced by Group A Streptococcus Vaccine Candidate J8-DT: Contribution of B and T-Cells Towards Protection

Vaccination with J8-DT, a leading GAS vaccine candidate, results in protective immunity in mice. Analysis of immunologic correlates of protection indicated a role of J8-specific antibodies that were induced post-immunization. In the present study, several independent experimental approaches were emp...

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Bibliographic Details
Main Authors: Pandey, Manisha, Batzloff, Michael R., Good, Michael F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660439/
https://ncbi.nlm.nih.gov/pubmed/19340309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005147
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