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LUMINAL Ca(2+) DEPLETION DURING THE UNFOLDED PROTEIN RESPONSE IN Xenopus OOCYTES: CAUSE AND CONSEQUENCE

The Endoplasmic Reticulum (ER) is a Ca(2+) storing organelle that plays a critical role in the synthesis, folding and post-translational modifications of many proteins. The ER enters into a condition of stress when the load of newly synthesized proteins exceeds its folding and processing capacity. T...

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Autors principals: Paredes, R. Madelaine, Bollo, Mariana, Holstein, Deborah, Lechleiter, James D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594557/
https://ncbi.nlm.nih.gov/pubmed/23415071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2013.01.002
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