Antitubercular pharmacodynamics of phenothiazines

OBJECTIVES: Phenothiazines have been shown to exhibit in vitro and in vivo activity against Mycobacterium tuberculosis (Mtb) and multidrug-resistant Mtb. They are predicted to target the genetically validated respiratory chain component type II NADH:quinone oxidoreductase (Ndh). Using a set of compo...

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Bibliografski detalji
Glavni autori: Warman, Ashley J., Rito, Teresa S., Fisher, Nicholas E., Moss, Darren M., Berry, Neil G., O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594496/
https://ncbi.nlm.nih.gov/pubmed/23228936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks483
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