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Engineering Escherichia coli for Soluble Expression and Single Step Purification of Active Human Lysozyme

Genetically engineered variants of human lysozyme represent promising leads in the battle against drug-resistant bacterial pathogens, but early stage development and testing of novel lysozyme variants is constrained by the lack of a robust, scalable and facile expression system. While wild type huma...

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Detalles Bibliográficos
Autores principales: Lamppa, John W., Tanyos, Sam A., Griswold, Karl E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594478/
https://ncbi.nlm.nih.gov/pubmed/23220215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2012.11.007
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