ATM POLYMORPHISMS PREDICT SEVERE RADIATION PNEUMONITIS IN PATIENTS WITH NON-SMALL CELL LUNG CANCER TREATED WITH DEFINITIVE RADIATION THERAPY

PURPOSE: The ataxia telangiectasia mutated (ATM) gene mediates detection and repair of DNA damage. We investigated associations between ATM polymorphisms and severe radiation-induced pneumonitis (RP). METHODS AND MATERIALS: We genotyped three potentially functional single nucleotide polymorphisms (S...

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Hlavní autoři: Xiong, Huihua, Liao, Zhongxing, Liu, Zhensheng, Xu, Ting, Wang, Qiming, Liu, Hongliang, Komaki, Ritsuko, Gomez, Daniel, Wang, Li-E, Wei, Qingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594431/
https://ncbi.nlm.nih.gov/pubmed/23154078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.09.024
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