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Abuse Liability and Reinforcing Efficacy of Oral Tramadol in Humans
BACKGROUND: Tramadol, a monoaminergic reuptake inhibitor, is hepatically metabolized to an opioid agonist (M1). This atypical analgesic is generally considered to have limited abuse liability. Recent reports of its abuse have increased in the U.S., leading to more stringent regulation in some states...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594406/ https://ncbi.nlm.nih.gov/pubmed/23098678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2012.09.018 |
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