NR5A2 Regulates Lhb and Fshb Transcription in Gonadotrope-Like Cells In Vitro, but Is Dispensable for Gonadotropin Synthesis and Fertility In Vivo

Successful mammalian reproduction depends on proper synthesis of the pituitary-derived glycoprotein hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Several transcription factors cooperate to activate cell-specific and hormone-regulated expression of the gonadotropin beta s...

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Detalhes bibliográficos
Main Authors: Fortin, Jérôme, Kumar, Vikas, Zhou, Xiang, Wang, Ying, Auwerx, Johan, Schoonjans, Kristina, Boehm, Ulrich, Boerboom, Derek, Bernard, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594184/
https://ncbi.nlm.nih.gov/pubmed/23536856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059058
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