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Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo

In Parkinson’s and Alzheimer’s diseases, the allocortex accumulates aggregated proteins such as synuclein and tau well before neocortex. We present a new high-throughput model of this topographic difference by microdissecting neocortex and allocortex from the postnatal rat and treating them in paral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Posimo, Jessica M., Titler, Amanda M., Choi, Hailey J. H., Unnithan, Ajay S., Leak, Rehana K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594169/
https://ncbi.nlm.nih.gov/pubmed/23536801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058596
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