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Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo

In Parkinson’s and Alzheimer’s diseases, the allocortex accumulates aggregated proteins such as synuclein and tau well before neocortex. We present a new high-throughput model of this topographic difference by microdissecting neocortex and allocortex from the postnatal rat and treating them in paral...

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Detalhes bibliográficos
Main Authors: Posimo, Jessica M., Titler, Amanda M., Choi, Hailey J. H., Unnithan, Ajay S., Leak, Rehana K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594169/
https://ncbi.nlm.nih.gov/pubmed/23536801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058596
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