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Neocortex and Allocortex Respond Differentially to Cellular Stress In Vitro and Aging In Vivo

In Parkinson’s and Alzheimer’s diseases, the allocortex accumulates aggregated proteins such as synuclein and tau well before neocortex. We present a new high-throughput model of this topographic difference by microdissecting neocortex and allocortex from the postnatal rat and treating them in paral...

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Autori principali: Posimo, Jessica M., Titler, Amanda M., Choi, Hailey J. H., Unnithan, Ajay S., Leak, Rehana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594169/
https://ncbi.nlm.nih.gov/pubmed/23536801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058596
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