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A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel
Both poikilotherms and homeotherms live longer at lower body temperatures, highlighting a general role of temperature reduction in lifespan extension. However, the underlying mechanisms remain unclear. One prominent model is that cold temperatures reduce the rate of chemical reactions, thereby slowi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594097/ https://ncbi.nlm.nih.gov/pubmed/23415228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.020 |
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