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A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel

Both poikilotherms and homeotherms live longer at lower body temperatures, highlighting a general role of temperature reduction in lifespan extension. However, the underlying mechanisms remain unclear. One prominent model is that cold temperatures reduce the rate of chemical reactions, thereby slowi...

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Detalhes bibliográficos
Main Authors: Xiao, Rui, Zhang, Bi, Dong, Yongming, Gong, Jianke, Xu, Tao, Liu, Jianfeng, Xu, X. Z. Shawn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594097/
https://ncbi.nlm.nih.gov/pubmed/23415228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.020
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