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Microglia and a Functional Type I IFN Pathway are Required to Counter HSV-1-Driven Brain Lateral Ventricle Enlargement and Encephalitis

HSV-1 is the leading cause of sporadic viral encephalitis with mortality rates approaching 30% despite treatment with the antiviral drug of choice, acyclovir. Permanent neurological deficits are common in patients that survive but the mechanism leading to this pathology is poorly understood impeding...

詳細記述

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書誌詳細
主要な著者: Conrady, Christopher D., Zheng, Min, van Rooijen, Nico, Drevets, Douglas A., Royer, Derek, Alleman, Anthony, Carr, Daniel J. J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594081/
https://ncbi.nlm.nih.gov/pubmed/23382563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203265
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