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Microglia and a Functional Type I IFN Pathway are Required to Counter HSV-1-Driven Brain Lateral Ventricle Enlargement and Encephalitis
HSV-1 is the leading cause of sporadic viral encephalitis with mortality rates approaching 30% despite treatment with the antiviral drug of choice, acyclovir. Permanent neurological deficits are common in patients that survive but the mechanism leading to this pathology is poorly understood impeding...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594081/ https://ncbi.nlm.nih.gov/pubmed/23382563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203265 |
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