Graft-versus-leukemia Effect of HLA-haploidentical Central-memory T-cells Expanded With Leukemic APCs and Modified With a Suicide Gene

Allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen (HLA)-haploidentical family donor (haplo-HSCT) is a readily available and potentially curative option for high-risk leukemia. In haplo-HSCT, alloreactivity plays a major role in the graft-versus-leukemia (GVL) e...

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Main Authors: Casucci, Monica, Perna, Serena Kimi, Falcone, Laura, Camisa, Barbara, Magnani, Zulma, Bernardi, Massimo, Crotta, Alessandro, Tresoldi, Cristina, Fleischhauer, Katharina, Ponzoni, Maurilio, Gregori, Silvia, Caligaris Cappio, Federico, Ciceri, Fabio, Bordignon, Claudio, Cignetti, Alessandro, Bondanza, Attilio, Bonini, Chiara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594033/
https://ncbi.nlm.nih.gov/pubmed/23299798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.227
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