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Chimeras reveal a single lipid-interface residue that controls MscL channel kinetics as well as mechanosensitivity

MscL, the highly conserved bacterial mechanosensitive channel of large conductance, functionally serves as an osmotic “emergency release valve”, is among the best studied mechanosensors and a paradigm of how a channel senses and responds to membrane tension. While all homologues tested thus far enco...

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Autors principals: Yang, Li-Min, Zhong, Dalian, Blount, Paul
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593973/
https://ncbi.nlm.nih.gov/pubmed/23416054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.018
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