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Chimeras reveal a single lipid-interface residue that controls MscL channel kinetics as well as mechanosensitivity
MscL, the highly conserved bacterial mechanosensitive channel of large conductance, functionally serves as an osmotic “emergency release valve”, is among the best studied mechanosensors and a paradigm of how a channel senses and responds to membrane tension. While all homologues tested thus far enco...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593973/ https://ncbi.nlm.nih.gov/pubmed/23416054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.018 |
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