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Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopy

Mechanical stress plays a key role in many genomic processes, such as DNA replication and transcription. The ability to predict the response of double-stranded (ds) DNA to tension is a cornerstone of understanding DNA mechanics. It is widely appreciated that torsionally relaxed dsDNA exhibits a stru...

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Auteurs principaux: King, Graeme A., Gross, Peter, Bockelmann, Ulrich, Modesti, Mauro, Wuite, Gijs J. L., Peterman, Erwin J. G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593895/
https://ncbi.nlm.nih.gov/pubmed/23431161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213676110
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