Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma is one of the most intractable and fatal cancer. The decreased blood vessel density displayed by this tumor not only favors its resistance to chemotherapy but also participates in its aggressiveness due to the consequent high degree of hypoxia. It is indeed clear tha...

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Detalhes bibliográficos
Main Authors: Guillaumond, Fabienne, Leca, Julie, Olivares, Orianne, Lavaut, Marie-Noëlle, Vidal, Nicolas, Berthezène, Patrice, Dusetti, Nelson Javier, Loncle, Céline, Calvo, Ezequiel, Turrini, Olivier, Iovanna, Juan Lucio, Tomasini, Richard, Vasseur, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593894/
https://ncbi.nlm.nih.gov/pubmed/23407165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219555110
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