Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma is one of the most intractable and fatal cancer. The decreased blood vessel density displayed by this tumor not only favors its resistance to chemotherapy but also participates in its aggressiveness due to the consequent high degree of hypoxia. It is indeed clear tha...

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Главные авторы: Guillaumond, Fabienne, Leca, Julie, Olivares, Orianne, Lavaut, Marie-Noëlle, Vidal, Nicolas, Berthezène, Patrice, Dusetti, Nelson Javier, Loncle, Céline, Calvo, Ezequiel, Turrini, Olivier, Iovanna, Juan Lucio, Tomasini, Richard, Vasseur, Sophie
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593894/
https://ncbi.nlm.nih.gov/pubmed/23407165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219555110
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