Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression

NMDA receptor (NMDAR) activation controls long-term potentiation (LTP) as well as long-term depression (LTD) of synaptic transmission, cellular models of learning and memory. A long-standing view proposes that a high level of Ca(2+) entry through NMDARs triggers LTP; lower Ca(2+) entry triggers LTD....

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Detalles Bibliográficos
Autores principales: Nabavi, Sadegh, Kessels, Helmut W., Alfonso, Stephanie, Aow, Jonathan, Fox, Rocky, Malinow, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593861/
https://ncbi.nlm.nih.gov/pubmed/23431133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219454110
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