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Alternate RNA splicing of murine nfkb1 generates a nuclear isoform of the p50 precursor NF-kappa B1 that can function as a transactivator of NF-kappa B-regulated transcription.

The NF-kappa B1 subunit of the transcription factor NF-kappa B is derived by proteolytic cleavage from the N terminus of a 105-kDa precursor protein. The C terminus of p105NF-kappa B1, like those of I kappa B proteins, contains ankyrin-related repeats that inhibit DNA binding and nuclear localizatio...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Grumont, R J, Fecondo, J, Gerondakis, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359385/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8460
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